AICAR

AICAR

AICAR peptides, the technical name of which is ribonucleotide 5-aminoimidazole-4-carboxamide. It is an intermediate substance contained in the production of inosine monophosphate. It acts primarily as an AMP-activated protein kinase agonist, which means that it has the ability to stimulate the action of nutrient stores for energy production.
What does it give you? Unprecedented endurance, protection of your heart and fat burning, which is extremely important in those sports that require maximum strength endurance (athletics, wrestling, crossfit, etc.).

Mechanism of action

AICAR is an adenosine analog that selectively activates activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis. AICAR can play a role in increasing these processes because it is able to penetrate into the heart. They block the production of enzymes related to the regulation of glucose consumption and the release of energy. By inhibiting these regulatory enzymes, cells can, in turn, increase the amount of glucose that can be obtained from fat, as well as increase the level of energy conversion. In addition, it was found that AIKAR is able to reduce programmed cell death - a process also called apoptosis.
AICAR is an analog of nucleosides that can enter nucleoside pools and significantly increase adenosine levels during periods of ATP decomposition. It has been established that adenosine regulation drugs (ARA) have therapeutic potential in myocardial ischemia.
Biological activity Cellular activity, allosteric activator of protein kinase, activated AMP (AMPK). Increased proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and decreased secretion of proinflammatory cytokines caused by psychosine and iNOS in astrocytes.
It should be noted that the biochemical processes that this product triggers have the same effects as during training. That's why AICAR got the nickname "training in a bottle". Even if you do not exercise, taking this product will provide the same effects at the biochemical level as during training, so you can maintain your fitness in case you missed a workout, as well as enhance the effect of the training.

Effects

• increased stamina;
• fat burning;
• heart protection;
• improvement of glucose metabolism;
• reducing the effects of ischemia;
• simulates the effect of physical activity at the biochemical level.